A year before the Battle of Sekigahara, the wandering ninja Saizo Kirigakure makes his living as an assassin and keeps everyone at arm's length. He crosses paths with Isanami, a shrine maiden fleeing the destruction of her temple, and reluctantly escorts her to the warlord Sanada Yukimura. Yukimura is gathering ten warriors of exceptional skill, the Sanada Ten Braves, and pulls Saizo and Isanami into his plans to shape the coming war.