Taisuke Kanou is a first-year high schooler in Tokyo who lives with his older sister Yoko, the nurse at his school, and spends his days with childhood friends Yuichi Hirose and Megumi Ochiai. Then a suicide virus reaches Earth, and within a week people are taking their own lives across the globe. A few of the survivors wake with strange abilities instead, Taisuke and Hirose among them, and the two are pulled into a hidden conflict among others like them.