Ichigo Momomiya and Masaya Aoyama have finally admitted their feelings for each other, only for the new relationship to be interrupted almost immediately by a fresh wave of Chimera Anima attacks. In the middle of one fight, a masked swordsman calling himself the Blue Knight appears out of nowhere to save Ichigo, declaring that protecting her is his purpose before vanishing again. Ichigo is left trying to balance her time with Masaya, her duties as leader of the Mew Mews, and the mystery of who the Blue Knight really is. This second season continues directly from the first season of Tokyo Mew Mew New.