During Japan's Warring States period, the samurai lord Daigo Kagemitsu strikes a bargain with 48 demons, offering pieces of his unborn son's body in exchange for the power to conquer the land. Born missing nearly all of those parts, the infant is abandoned, then found and raised by a healer who fits him with prosthetics and names him Hyakkimaru. As a young man, Hyakkimaru sets out with a scrappy orphan thief named Dororo, hunting the demons one by one to reclaim what was taken from his body. This manga retells the original Dororo for a new generation of readers.