Red Blood Cell AA2153 reports for his first day inside a human body wrecked by smoking, drinking and stress, and finds a workplace nothing like the one in the textbooks. Arteries are choked with cholesterol, oxygen runs short, and the neutrophil White Blood Cell U-1196 spends every shift fighting infections the body keeps inviting in. This spin-off moves the anthropomorphic-cell premise of Cells at Work! from a healthy body to an adult one in steady decline.