Vampire hunts are sweeping the United States, and a rumor spreads among the hunted: Mina Tepes has summoned every vampire in America, and anyone who reaches the West Coast will be shipped to the Vampire Bund. The rumor has a problem, since the Bund sank months ago and its queen is reported dead. Jessica and her daughter Susy run a caravan from New York to Los Angeles regardless, smuggling a vampire family and their human daughter past militia checkpoints toward the promised ship, while Mina's werewolf bodyguard Akira remains somewhere in the picture.