Shuichi Nitori and Yoshino Takatsuki start their first year of middle school sharing a secret each keeps from almost everyone else: Shuichi wants to live as a girl, and Yoshino wants to be a boy. New uniforms and new classmates make that harder, while their circle from elementary school stays close by, with Saori Chiba quietly attached to Shuichi and Kanako Sasa smoothing over every quarrel. Puberty arrives on its own schedule, and neither of them can slow it down.