The renegade priest Genjo Sanzo, nothing like the holy man his rank implies, is ordered west across Shangri-La to stop the resurrection of the demon Gyumaoh, whose revival has loosed a Minus Wave driving the region's yokai to madness. Three of them travel with him: the monkey king Son Goku, the half-demon flirt Sha Gojyo, and the gentle Cho Hakkai, who carries a heavy past. The journey, a loose retelling of Journey to the West, throws assassins and their own histories across their path.